Fri Mar 10 2023

48 articles - From Friday Mar 03 2023 to Friday Mar 10 2023

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Liver Transpl

Systematic review and meta-analysis of open versus laparoscopy-assisted versus pure laparoscopic versus robotic living donor hepatectomy.

There seems to be a marginal benefit in EBL and/or LOS in favor of PLLDH and RLDH. The complexity of these procedures limits them to transplant centers with high volume and experience. Future studies should investigate self-reported donor experience and the associated economic costs of these approaches.

Pubmed   Journal   ReadQx 


Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

A linear programming based method for designing menus for controlled feeding trials.

The model helps to design menus in a fast, objective, transparent, and reproducible way. It greatly facilitates the design procedure for menus in controlled feeding trials and lowers development costs.

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Association between blood N-3 fatty acid levels and the risk of coronavirus disease 2019 in the UK Biobank.

These findings suggest that nutritional strategies to increase the circulating n-3 PUFA levels, such as increased consumption of oily fish and/or use of n-3 FA supplements, may reduce the risk of adverse COVID-19 outcomes.

Pubmed   Journal   ReadQx   PMC

Healthy dietary patterns are associated with the gut microbiome in the Hispanic Community Health Study/Study of Latinos.

Healthy dietary patterns in this population are associated with a higher abundance of fiber-fermenting Clostridia species in the gut microbiome, consistent with previous studies in other racial/ethnic groups. Gut microbiota may be involved in the beneficial effect of higher diet quality on cardiometabolic disease risk.

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Infant blood concentrations of folate markers and catabolites are modified by 5,10-methylenetetrahydrofolate reductase C677T genotype and dietary folate source.

Folate intake from infant formula according to the present EU legislation increased RBC folate and plasma pABG concentrations in infants to a greater extent than breastfeeding, particularly in carriers of the TT genotype. However, this intake did not completely abolish the between-genotype differences in pABG. Whether these differences have any clinical relevance, however, remains unclear.

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Long-term adherence to healthful and unhealthful plant-based diets and breast cancer risk overall and by hormone receptor and histologic subtypes among postmenopausal females.

Long-term adherence to healthful plant foods with some intake of unhealthy plant and animal foods may reduce BC risk with an optimal risk reduction in the moderate intake range. Adherence to an unhealthful plant-based diet may increase BC risk. These results emphasize the importance of the quality of plant foods for cancer prevention.

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Low calf circumference adjusted for body mass index is associated with prolonged hospital stay.

BMI-adjusted low CC was identified in more than 60% of hospitalized patients and was an independent predictor of longer LOS.

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Maternal hemoglobin levels and adverse pregnancy outcomes: individual patient data analysis from 2 prospective UK pregnancy cohorts.

Higher maternal Hb may identify the risk of adverse pregnancy outcomes. Further research is required to investigate if this association is causal and to identify the underlying mechanisms.

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Natural language processing and machine learning approaches for food categorization and nutrition quality prediction compared with traditional methods.

Our automation achieved high accuracy in classifying food categories and predicting nutrition quality scores using text information found on food labels. This approach is effective and generalizable in a dynamic food environment, where large amounts of food label data can be obtained from websites.

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Novel approaches to examining weight change in pregnancies affected by obesity.

Among pregnancies affected by obesity, GWC was not linear or uniform. Different patterns of high gain were associated with increased risk for LGA with the greatest magnitude in obesity grade 2, while GWC patterns were not associated with SGA. Research registration This research does not require registration at clinicaltrials.gov.

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Nutrient-sensitive approach for sustainability assessment of Australian macronutrient dietary recommendations.

We conclude that encouraging consumers to adhere to the lower limit of the recommended intake of proteins and meeting the protein requirement through protein-dense plant sources could improve dietary environmental and economic sustainability in Australia. Our findings provide a means of understanding the sustainability of dietary recommendations concerning macronutrients for any country where input-output databases are available.

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Plant-based diets and the risk of pancreatic cancer: a large prospective multicenter study.

In this US population, adherence to a healthy plant-based diet confers a lower risk of pancreatic cancer, whereas adherence to a less healthy plant-based diet confers a higher risk. These findings highlight the importance of considering plant food quality in preventing pancreatic cancer.

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PNPLA3 genotypes modify the adverse effect of the total energy intake on high-risk nonalcoholic steatohepatitis development.

The total energy intake adversely affected the development of high-risk NASH in patients with biopsy-confirmed NAFLD. The effect was more prominent in patients without the PNPLA3 risk allele, highlighting the importance of personalized dietary interventions in NAFLD treatment.

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Popular diets as selected by adults in the United States show wide variation in carbon footprints and diet quality.

Our results highlight the nuances when evaluating the nutritional quality of diets and their carbon footprints. On average, pescatarian diets may be the healthiest, but plant-based diets have lower carbon footprints than other popular diets, including keto- and paleo-style diets.

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Racial and ethnic heterogeneity in diets of low-income adult females in the United States: results from National Health and Nutrition Examination Surveys from 2011 to 2018.

Differences among the consumption behaviors of low-income female adults were found along racial and ethnic lines. Efforts to improve the nutritional health of low-income female adults should consider racial and ethnic differences in diets to appropriately focus interventions.

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The effect of modest changes in sleep on dietary intake and eating behavior in children: secondary outcomes of a randomized crossover trial.

Mild sleep deprivation may play a role in pediatric obesity by increasing caloric intake, particularly from noncore and ultraprocessed foods. Eating in response to emotions rather than perceived hunger may partly explain why children engage in unhealthy dietary behaviors when tired.

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Total energy expenditure as assessed by doubly-labeled water and all-cause mortality in a cohort of postmenopausal females.

Higher energy expenditure is associated with higher all-cause mortality among younger postmenopausal females, only partially explained by weight and weight change. This study is registered with clinicaltrials.gov identifier NCT00000611.

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Weight gain in pregnancy and infant birthweight after the onset of the COVID-19 pandemic: an interrupted time series analysis.

We observed a modest increase in weight gain after the onset of the pandemic among pregnant people but no changes in infant birthweights. This weight change could be more important in high BMI subgroups.

Pubmed   Journal   ReadQx   PMC

Inflamm Bowel Dis

Are the New Biologics Effective in the Management of Postoperative Crohn's Disease?

The newer biologics do play a role in the management of postoperative Crohn's disease. After our review, we proposed an updated algorithm on the role of newer biologics in the approach to patients with postoperative Crohn's disease. Yet, until we have better-designed studies, their definite positioning remains to be determined.

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Risk of Tuberculosis and Hepatitis B Reactivation in Patients With Crohn's Disease on Ustekinumab: A Nationwide Real-World Study.

UST was safe for treatment of CD because no patient developed tuberculosis, persistent hepatitis, or acute liver failure during therapy, whether with a prophylactic regimen or not, based on our sample size and limited follow-up time.

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J Crohns Colitis

Diagnosis and Clinical Features of Perianal Lesions in Newly Diagnosed Crohn's Disease: Subgroup Analysis from Inception Cohort Registry Study of Patients with Crohn's Disease (iCREST-CD).

At the time of CD diagnosis, approximately half of the patients had perianal lesions; perianal abscesses and perianal fistulas were the most common. Young age, male sex, disease location, and behaviour are significantly associated with the presence of perianal lesions. The presence of perianal lesion was associated with fatigue and impairment of daily activities.

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Intestinal epithelial cell-specific deletion of cytokine-inducible SH2- containing protein alleviates experimental colitis in ageing mice.

CISH might be a proinflammatory regulator in ageing; therefore, targeted therapy against CISH may provide a novel strategy for treating ageing-related IBD.

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Liver Transpl

An extensive evaluation of hepatic markers of damage and regeneration in controlled and uncontrolled donation after circulatory death.

In conclusion, despite initial differences in liver damage biomarkers, uDCD group was characterized by a major gene expression of regenerative and repair factors after the NRP procedure. Correlative analysis among circulating/tissue biomarkers and the tissue congestion/necrosis degree, revealed new potential candidate biomarkers.

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Cardiac index and hepatopulmonary syndrome in liver transplantation candidates: The Pulmonary Vascular Complications of Liver Disease Study.

HPS was associated with higher CI among LT candidates. Independent of HPS, higher CI was associated with increased dyspnea and worse functional class, QOL, and arterial oxygenation.

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Positron emission tomography myocardial perfusion imaging (PET MPI) findings predictive of post-liver transplant major adverse cardiac events.

Nearly 20% of LT recipients experienced MACE within the first 12 months of LT. Reduced global MFR and reduced resting LVEF on PET MPI among LT candidates were associated with increased risk of post-LT MACE. Awareness of these PET-MPI parameters may help improve cardiac risk stratification of LT candidates if confirmed in future studies.

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Post-transplant outcomes for alcohol-associated liver disease during the COVID-19 pandemic.

¦¦¦¦. Karthik Goli, Peter Lymberopoulos: Authors contributed equally.

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Pancreatology

Involvement of transverse mesocolon is associated with development of colonic fistula in patients with acute necrotizing pancreatitis.

TM involvement in ANP patients is associated with development of colonic fistula in ANP patients.

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Prospective evaluation of an emergency department protocol to prevent hospitalization in mild acute pancreatitis: Outcomes and predictors of discharge.

After appropriate triage, patients with mild AP (age <50, CCI <2, idiopathic AP) can safely discharge from the ED with improved outcomes and cost savings.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr

Bioactive omega-3 fatty acids are associated with reduced risk and severity of SARS-CoV-2 infection.

Pubmed   Journal   ReadQx   PMC

Delaying children's bedtime affects food intake and is related to emotions rather than satiety.

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Diversifying nutritional sciences-dietary practices and gut bacteria in individuals of Latino and Hispanic ancestry.

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Establishing dietary reference intakes and laboratory reference ranges for folate-maybe not so simple for infants.

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For breast cancer prevention, not all plant-based diets are created equal.

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Let's do the math: embracing mathematical modeling to advance nutrition research.

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Natural language processing: fast forwarding research to the "good stuff": Natural language processing for nutrition.

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Pancreatic cancer: Are all plant-based diets the same?

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Quasi-experimental study designs can inform pandemic effects on nutrition and weight gain in pregnancy.

Pubmed   Journal   ReadQx   PMC

Unpacking perplexing findings on maternal hemoglobin and pregnancy outcomes: call for further research to understand underlying etiology and mechanisms.

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Inflamm Bowel Dis

To Be in Remission or in Corticosteroid-free Remission: That Is the Question for Women With Inflammatory Bowel Disease at Conception.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Automated Clinical Pathway Utilizing Custom Risk Stratification Identifies Substantial Rates of Overdue Follow-up Among Patients With Inflammatory Bowel Disease and Facilitates Population Health Interventions.

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Oral Vancomycin Induced and Maintained Clinical and Endoscopic Remission in Ulcerative Colitis and Primary Sclerosing Cholangitis Post-liver Transplantation.

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Shedding New Light on High-Risk Phenotypes for Pouchitis.

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Liver Transpl

Policy corner: ischemic cholangiopathy associated with donation after cardiac death.

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Post-liver transplant acute cardiomyopathy: role of prospective cardiac evaluation in immediate post-transplant period.

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Short- and long-term outcomes of donor and recipient in living donor liver transplantation using variant grafts.

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Single dose eculizumab as part of a modified desensitization protocol for abo-incompatible living donor liver transplantation.

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Letters&Replies

Letters to the editors and authors’ replies

Am J Clin Nutr

Bioimpedance for assessing adiposity: The importance of comparisons.

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Convincing experimental data is required to revisit the passive overconsumption hypothesis.

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